卞平艳, 石建功, 王跃宇,等.超声激励对微压印PPDO血管支架的力学性能影响研究[J].河南理工大学学报（自然科学版）,2022,41(4):89-94.

BIAN P Y, SHI J G, WANG Y Y,et al.Study on the effect of ultrasonic excitation on the mechanical properties of micro-embossing PPDO vascular stent[J].Journal of Henan Polytechnic University(Natural Science) ,2022,41(4):89-94.

超声激励对微压印PPDO血管支架的力学性能影响研究

卞平艳1, 石建功1, 王跃宇2, 李瑜1, 王建平1

1.河南理工大学 机械与动力工程学院，河南 焦作454000;2.鸿富锦精密电子有限公司，河南 郑州 451162

摘要:为了使血管支架获得更高的径向支撑强度，防止血管修复时发生再狭窄，比较了微压印和超声微压印两种工艺对聚对二氧环己酮（PPDO ）血管支架成型性能及结晶行为的影响。 EM检测发现，相同条件（温度，压力）下，超声微压印支架的球晶密度大，球晶细化，填充效果好，复制精度高；力学性能测试结果表明，超声微压印支架平均径向支撑强度提高约30％ XRD分析结果显示，两种工艺成型的支架与标准PPDO材料XRD图谱谱线的峰位相一致，都在相同位置（21°左右）出现最强衍射峰，超声微压印支架的最强衍射峰峰形相对展宽，说明超声激励作用机制提高了结晶度。超声激励有助于提高结晶度和细化晶粒，对聚合物的力学性能提升显著，有望在相同甚至更小厚度条件下，获得更高的径向支撑强度。

关键词:聚对二氧环己酮;血管支架;超声微压印;球晶;径向支撑强度;结晶行为

doi:10.16186/j.cnki.1673-9787.2020090085

基金项目:国家自然科学基金资助项目（31370999）；河南省自然科学基金资助项目（222300410447）；河南省高校基本科研业务费专 项项目（NSFRF210341）；河南理工大学博士基金资助项目（B2017-029 ，B2013-025 ）

收稿日期:2020/09/19

修回日期:2021/03/03

出版日期:2022/07/15

Study on the effect of ultrasonic excitation on the mechanical properties of micro-embossing PPDO vascular stent

BIAN Pingyan1, SHI Jiangong1, WANG Yueyu2, LI Yu1, WANG Jianping1

1.School of Mechanical and Power Engineering， Henan Polytechnic University， Jiaozuo 454000 ， Henan， China;2.Cloud Enterprise Solutions Business Group， Zhengzhou  451162 ， Henan， China

Abstract: In order to obtain higher radial support strength of the vascular stent and to prevent restenosis during vascular repair,the influences of micro-embossing and ultrasonic micro-embossing on the forming performance and crystallization behaviour of poly ( p-dioxanone) (PPDO) vascular stent were compared in this paper. SEM inspection showed that under the same conditions ( temperature , pressure ) ,the stent of high spherulites density , refined spherulites , good filling effect and high replication accuracy were obtained by using ultrasonic micro-embossing. The mechanical performance test results showed that the radial support strength of the ultrasonic micro-embossing stent was increased by about 30% on average. The XRD analysis results indicated that the stents formed by the two processes were consistent with the peak positions of the standard PPDO material in XRD pattern,and both appeared at the same position (about 21°) with the strongest diffraction peaks. The peak shape of the strongest diffraction peak appearing on the ultrasonic micro-embossing stent was relatively sharper and the peak surface was larger,this revealed that the mechanism of ultrasonic excitation was to increase the crystallinity rather than to trigger the appearance of a new crystal structure of PPDO. Through the ultrasonic excitation , crystallinity was improved, crystal grains were refined,and mechanical properties of polymers were promoted significantly. It was expected to obtain higher radial support strength with the same or even smaller thickness.

Key words:poly （p-dioxanone ）;vascular stent;ultrasonic micro-embossing;spherulite;radial support strength;crystallization behaviour

超声激励对微压印PPDO血管支架的力学性能影响研究_卞平艳.pdf